Buckingham Palace announced on Monday that the king will meet local communities in the city he first visited in 2002 when still a prince.
He later returned in 2008 where he played a pivotal role in establishing the Kraków branch of the Jewish Community Center (JCC).
Jonathan Ornstein, director of the Kraków JCC, told Gazeta Krakowska: “It was a great honor for me - after all, without him there would not be our organization.
“If it weren't for his help, I don't know what the future of the Jewish community in Kraków would look like.”
He added that the JCC maintains a strong relationship with Buckingham Palace.
“Every six months, every year, we get information from the palace that Charles asks for a report... It's not that he formed the JCC and stopped taking an interest in our community - we have this contact and maintain it,” he said.
The king will later travel 68km to the site of the former Nazi death camp to attend a commemorative service.
Over 1.1 million people, predominantly Jews, were murdered at Auschwitz, along with Poles, Roma, and Sinti.
The king is also scheduled to meet Polish President Andrzej Duda.
Ahead of his visit on January 27, King Charles hosted a Holocaust education event on Monday where he met 94-year-old Holocaust survivor Manfred Goldberg.
Goldberg’s testimony was recorded for interactive lessons aimed at educating students about the Holocaust.
The king also paid tribute to Holocaust victims and those of more recent genocides by lighting a commemorative candle.
The event included a demonstration of an AI-powered platform that allows students to interactively learn from survivors and concluded with a musical performance inspired by the experiences of British Holocaust survivors.